Isolithocholic Acid

CAS No. 1534-35-6

Isolithocholic Acid( —— )

Catalog No. M34789 CAS No. 1534-35-6

Isolithocholic Acid (3-Epilithocholic acid) (β-Lithocholic acid) is an isomer of Lithocholic acid.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 185 Get Quote
5MG 353 Get Quote
10MG 522 Get Quote
25MG 799 Get Quote
50MG 1076 Get Quote
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Biological Information

  • Product Name
    Isolithocholic Acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Isolithocholic Acid (3-Epilithocholic acid) (β-Lithocholic acid) is an isomer of Lithocholic acid.
  • Description
    Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate.
  • In Vitro
    Isolithocholic acid at 0.01 % does not inhibit spore germination and outgrowth of CF5 and M120, but it significantly inhibits at the higher concentration (0.1 %). Isolithocholic acid (0.00003 %) prevents growth of CD196, M68, CF5, 630, and BI9 and significant decreases strains CF5, BI9, M120, and 630 in toxin activity. Isolithocholic acid (0.0003 %) makes that all strains displays a significant decrease in toxin activity, except for R20291 and M120.
  • In Vivo
    The levels of fecal Isolithocholic acid shows obvious decreases from day 28 onward in the high fat diet (HFD) group compared with rats fed a normal diet.
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1534-35-6
  • Formula Weight
    376.57
  • Molecular Formula
    C24H40O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 28.57 mg/mL (75.87 mM; Ultrasonic )
  • SMILES
    [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Batta AK, et al. Transformation of bile acids into iso-bile acids by Clostridium perfringens: possible transport of 3 beta-hydrogen via the coenzyme. Hepatology. 1985;5(6):1126-1131.?
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